Cephaeline promotes ferroptosis by targeting NRF2 to exert anti-lung cancer efficacy

AbstractContext Cephaeline is a natural product isolated from ipecac (Cephaelis ipecacuanha [Brot.] A. Rich. [Rubiaceae]). It exhibits promising anti-lung cancer activity and ferroptosis induction may be a key mechanism for its anti-lung cancer effect.Objectives This study investigates the anti-lung...

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Bibliographic Details
Main Authors: Peng Chen, Qingxuan Ye, Shang Liang, Linghui Zeng
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Pharmaceutical Biology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2024.2309891