Regulation of pancreatic stellate cell activation by Notch3

Abstract Background Activated pancreatic stellate cells (PaSCs) are the key cellular source of cancer-associated fibroblasts in the pancreatic stroma of patients with pancreatic ductal adenocarcinoma (PDAC), however, the activation mechanism of PaSCs is not yet known. The Notch signaling pathway, co...

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Bibliographic Details
Main Authors: Haiyan Song, Yuxiang Zhang
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-017-3957-2