Genomic landscape of clinically advanced KRAS wild-type pancreatic ductal adenocarcinoma

Genomic landscape of clinically advanced KRAS wild-type pancreatic ductal adenocarcinoma

IntroductionKRAS mutation is a common occurrence in Pancreatic Ductal Adenocarcinoma (PDA) and is a driver mutation for disease development and progression. KRAS wild-type PDA may constitute a distinct molecular and clinical subtype. We used the Foundation one data to analyze the difference in Genom...

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Bibliographic Details
Main Authors: Prashanth Ashok Kumar, Serenella Serinelli, Daniel J. Zaccarini, Richard Huang, Natalie Danziger, Tyler Janovitz, Alina Basnet, Abirami Sivapiragasam, Stephen Graziano, Jeffrey S. Ross
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
pancreatic ductal adenocarcinoma
KRAS mutation
KRAS wild-type pancreatic cancer
genomic alterations
targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1169586/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1169586/full

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