Dynein Light Chain 1 (DYNLT1) Interacts with Normal and Oncogenic Nucleoporins.

The chimeric oncoprotein NUP98-HOXA9 results from the t(7;11)(p15;p15) chromosomal translocation and is associated with acute myeloid leukemia. It causes aberrant gene regulation and leukemic transformation through mechanisms that are not fully understood. NUP98-HOXA9 consists of an N-terminal porti...

Full description

Bibliographic Details
Main Authors: Nayan J Sarma, Nabeel R Yaseen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3694108?pdf=render