Urinary Cysteinyl Leukotrienes as Biomarkers of Endothelial Activation, Inflammation and Oxidative Stress and Their Relationship with Organ Dysfunction in Human Septic Shock

Urinary Cysteinyl Leukotrienes as Biomarkers of Endothelial Activation, Inflammation and Oxidative Stress and Their Relationship with Organ Dysfunction in Human Septic Shock

Cysteinyl leukotrienes (CysLT) are potent vascular leakage-promoting agents but have been scarcely explored in human septic shock (SS). We evaluated CysLT at admission and during hospitalization and their correlation with endothelial dysfunction, inflammation, oxidative stress, the renin–angiotensin...

Full description

Bibliographic Details
Main Authors: Marta Reina-Couto, Marisa Santos-Oliveira, Patrícia Pereira-Terra, Carolina Silva-Pereira, Janete Quelhas-Santos, Álvaro Duarte, Sandra Martins, Paula Serrão, Cláudia Camila Dias, Manuela Morato, João T. Guimarães, Roberto Roncon-Albuquerque, José-Artur Paiva, António Albino-Teixeira, Teresa Sousa
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomedicines
Subjects:
cysteinyl leukotrienes
septic shock
endothelial activation
inflammation
oxidative stress
organ dysfunction
Online Access:https://www.mdpi.com/2227-9059/10/11/2845

Internet

https://www.mdpi.com/2227-9059/10/11/2845

Similar Items