Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy

Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy

Abstract Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account for the high mortality rate. The tumor microenvironment (TME) conta...

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Bibliographic Details
Main Authors: Ajaz A. Bhat, Sabah Nisar, Selma Maacha, Tatiana Correa Carneiro-Lobo, Sabah Akhtar, Kodappully Sivaraman Siveen, Nissar A. Wani, Arshi Rizwan, Puneet Bagga, Mayank Singh, Ravinder Reddy, Shahab Uddin, Jean-Charles Grivel, Gyan Chand, Michael P. Frenneaux, Mushtaq A. Siddiqi, Davide Bedognetti, Wael El-Rifai, Muzafar A. Macha, Mohammad Haris
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Molecular Cancer
Subjects:
Esophageal cancer
Cytokines
Chemokines
Inflammation
Tumor microenvironment
Epithelial-Mesenchymal transition
Online Access:https://doi.org/10.1186/s12943-020-01294-3

Internet

https://doi.org/10.1186/s12943-020-01294-3

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