ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration
Stress response JNK signalling is important for cell death-induced regeneration. Here the authors show in adultDrosophilaenterocytes that ATF3 regulates the expression of Raw, a JNK antagonist, to control intestinal regeneration and barrier function in response to infection.
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms14289 |