Potential selection of antimony and methotrexate cross-resistance in Leishmania infantum circulating strains.

<h4>Background</h4>Visceral leishmaniasis (VL) resolution depends on a wide range of factors, including the instauration of an effective treatment coupled to a functional host immune system. Patients with a depressed immune system, like the ones receiving methotrexate (MTX), are at highe...

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Bibliographic Details
Main Authors: Lorena Bernardo, Ana Victoria Ibarra-Meneses, Noelie Douanne, Audrey Corbeil, Jose Carlos Solana, Francis Beaudry, Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0012015&type=printable