Structural dynamics reveal isolate-specific differences at neutralization epitopes on HIV Env

Structural dynamics reveal isolate-specific differences at neutralization epitopes on HIV Env

Summary: The envelope glycoprotein (Env) is the sole target for neutralizing antibodies against HIV and the most rapidly evolving, variable part of the virus. High-resolution structures of Env trimers captured in the pre-fusion, closed conformation have revealed a high degree of structural similarit...

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Váldodahkkit: Edgar A. Hodge, Gajendra S. Naika, Sally M. Kephart, Adam Nguyen, Richard Zhu, Mark A. Benhaim, Wenjin Guo, John P. Moore, Shiu-Lok Hu, Rogier W. Sanders, Kelly K. Lee
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Elsevier 2022-06-01
Ráidu:iScience
Fáttát:
Immunology
Microbiology
Structural biology
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2589004222007209

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http://www.sciencedirect.com/science/article/pii/S2589004222007209

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