ASC nanobodies to counteract the consequences of inflammasome activation

Abstract Inflammasomes are multiprotein complexes that signal by oligomerizing the apoptosis speck‐like protein with caspase recruitment and activator domain (ASC) and are involved in multiple inflammatory, metabolic and degenerative diseases. Pharmacological targeting of specific inflammasomes with...

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Bibliographic Details
Main Authors: Sahil Adriouch, Pablo Pelegrin
Format: Article
Language:English
Published: Springer Nature 2022-05-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.202216087