ASC nanobodies to counteract the consequences of inflammasome activation
Abstract Inflammasomes are multiprotein complexes that signal by oligomerizing the apoptosis speck‐like protein with caspase recruitment and activator domain (ASC) and are involved in multiple inflammatory, metabolic and degenerative diseases. Pharmacological targeting of specific inflammasomes with...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2022-05-01
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Series: | EMBO Molecular Medicine |
Online Access: | https://doi.org/10.15252/emmm.202216087 |