Reading and Misreading 8-oxoguanine, a Paradigmatic Ambiguous Nucleobase

Reading and Misreading 8-oxoguanine, a Paradigmatic Ambiguous Nucleobase

7,8-Dihydro-8-oxoguanine (oxoG) is the most abundant oxidative DNA lesion with dual coding properties. It forms both Watson&#8722;Crick (<i>anti</i>)oxoG:(<i>anti</i>)C and Hoogsteen (<i>syn</i>)oxoG:(<i>anti</i>)A base pairs without a significant...

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Bibliographic Details
Main Authors: Anna V. Yudkina, Evgeniy S. Shilkin, Anton V. Endutkin, Alena V. Makarova, Dmitry O. Zharkov
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Crystals
Subjects:
7,8-Dihydro-8-oxoguanine
mutagenesis
DNA polymerases
base excision repair
DNA glycosylases
nucleotide hydrolases
translesion DNA synthesis
Online Access:https://www.mdpi.com/2073-4352/9/5/269

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https://www.mdpi.com/2073-4352/9/5/269

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