Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells

Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells

Show other versions (1)

Humans are infected with two types of EBV (Type 1 (T1) and Type 2 (T2)) that differ substantially in their EBNA2 and EBNA 3A/B/C latency proteins and have different phenotypes in B cells. T1 EBV transforms B cells more efficiently than T2 EBV in vitro, and T2 EBV-infected B cells are more lytic. We...

Full description

Bibliographic Details
Main Authors: Jillian A. Bristol, Joshua Brand, Makoto Ohashi, Mark R. Eichelberg, Alejandro Casco, Scott E. Nelson, Mitchell Hayes, James C. Romero-Masters, Dana C. Baiu, Jenny E. Gumperz, Eric C. Johannsen, Huy Q. Dinh, Shannon C. Kenney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-04-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041801/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041801/?tool=EBI

Similar Items