Chemiluminescent screening of specific hybridoma cells via a proximity-rolling circle activated enzymatic switch

In order to realize fast screening of specific hybridoma cells in hybridoma technology, a 1-day chemiluminescent screening method is reported on common 96-well plate via a proximity-rolling circle activated enzymatic switch strategy.

Bibliographic Details
Main Authors: Hang Ao, Weiwei Chen, Jie Wu, Wencheng Xiao, Huangxian Ju
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03283-2