Ectopic ATP synthase stimulates the secretion of extracellular vesicles in cancer cells

Abstarct Ectopic ATP synthase on the plasma membrane (eATP synthase) has been found in various cancer types and is a potential target for cancer therapy. However, whether it provides a functional role in tumor progression remains unclear. Here, quantitative proteomics reveals that cancer cells under...

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Bibliographic Details
Main Authors: Yi-Chun Kao, Yi-Wen Chang, Charles P. Lai, Nai-Wen Chang, Chen-Hao Huang, Chien-Sheng Chen, Hsuan-Cheng Huang, Hsueh-Fen Juan
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05008-5