Artificial Digestion of Polydisperse Copper Oxide Nanoparticles: Investigation of Effects on the Human In Vitro Intestinal Co-Culture Model Caco-2/HT29-MTX

Artificial Digestion of Polydisperse Copper Oxide Nanoparticles: Investigation of Effects on the Human In Vitro Intestinal Co-Culture Model Caco-2/HT29-MTX

Copper oxide nanoparticles (CuO-NP) are increasingly used in consumer-related products, which may result in increased oral ingestion. Digestion of particles can change their physicochemical properties and toxicity. Therefore, our aim was to simulate the gastrointestinal tract using a static in vitro...

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Bibliographic Details
Main Authors: Jevin Büttner, Thomas Schneider, Martin Westermann, Michael Glei
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Toxics
Subjects:
static in vitro digestion
copper oxide nanoparticles
intestinal barrier integrity
cell viability
apoptosis
delivered dose
Online Access:https://www.mdpi.com/2305-6304/10/3/130

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https://www.mdpi.com/2305-6304/10/3/130

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