CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue

CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue

Summary: Adipose-derived stem cells (ASCs) drive healthy visceral adipose tissue (VAT) expansion via adipocyte hyperplasia. Obesity induces ASC senescence that causes VAT dysfunction and metabolic disorders. It is challenging to restrain this process by biological intervention, as mechanisms of cont...

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Bibliographic Details
Main Authors: Zixin Zhou, Huiying Zhang, Yan Tao, Haipeng Jie, Jingyuan Zhao, Jinhao Zang, Huijie Li, Yalin Wang, Tianci Wang, Hui Zhao, Yuan Li, Chun Guo, Faliang Zhu, Haiting Mao, Lining Zhang, Fengming Liu, Qun Wang
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723004357

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http://www.sciencedirect.com/science/article/pii/S2211124723004357

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