Further Association of Germline <i>CHEK2</i> Loss-of-Function Variants with Testicular Germ Cell Tumors

Testicular germ cell tumors (TGCTs) represent the most frequent malignancy in young adult men and have one the highest heritability rates among all cancers. A recent multicenter case–control study identified <i>CHEK2</i> as the first moderate-penetrance TGCT predisposition gene. Here, we...

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Bibliographic Details
Main Authors: Kira Kirchner, Christoph Seidel, Finn-Ole Paulsen, Bianca Sievers, Carsten Bokemeyer, Davor Lessel
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/12/22/7065