Diacylglycerol kinase-ε is S-palmitoylated on cysteine in the cytoplasmic end of its N-terminal transmembrane fragment

Diacylglycerol kinase-ε is S-palmitoylated on cysteine in the cytoplasmic end of its N-terminal transmembrane fragment

Diacylglycerol kinase-ε (DGKε) catalyzes phosphorylation of diacylglycerol to phosphatidic acid with a unique specificity toward 1-stearoyl-2-arachidonoyl-sn-glycerol, which is a backbone of phosphatidylinositol (PI). Owing to this specificity, DGKε is involved in the PI cycle maintaining the cellul...

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Bibliographic Details
Main Authors: Gabriela Traczyk, Aneta Hromada-Judycka, Anna Świątkowska, Julia Wiśniewska, Anna Ciesielska, Katarzyna Kwiatkowska
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Lipid Research
Subjects:
atypical hemolytic uremic syndrome
cell signaling
diacylglycerol kinase
kinase activity assay
lipids/chemistry
palmitoylation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227523001530

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http://www.sciencedirect.com/science/article/pii/S0022227523001530

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