Detecting the immune system response of a 500 year-old Inca mummy.

Disease detection in historical samples currently relies on DNA extraction and amplification, or immunoassays. These techniques only establish pathogen presence rather than active disease. We report the first use of shotgun proteomics to detect the protein expression profile of buccal swabs and clot...

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Bibliographic Details
Main Authors: Angelique Corthals, Antonius Koller, Dwight W Martin, Robert Rieger, Emily I Chen, Mario Bernaski, Gabriella Recagno, Liliana M Dávalos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3405130?pdf=render