Voltage sensor current, SR Ca2+ release, and Ca2+ channel current during trains of action potential‐like depolarizations of skeletal muscle fibers

Abstract In skeletal muscle, CaV1.1 serves as the voltage sensor for both excitation‐contraction coupling (ECC) and L‐type Ca2+ channel activation. We have recently adapted the technique of action potential (AP) voltage clamp (APVC) to monitor the current generated by the movement of intramembrane v...

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Bibliographic Details
Main Authors: Hugo Bibollet, Elton L. Nguyen, Daniel R. Miranda, Christopher W. Ward, Andrew A. Voss, Martin F. Schneider, Erick O. Hernández‐Ochoa
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15675