Voltage sensor current, SR Ca2+ release, and Ca2+ channel current during trains of action potential‐like depolarizations of skeletal muscle fibers
Abstract In skeletal muscle, CaV1.1 serves as the voltage sensor for both excitation‐contraction coupling (ECC) and L‐type Ca2+ channel activation. We have recently adapted the technique of action potential (AP) voltage clamp (APVC) to monitor the current generated by the movement of intramembrane v...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-05-01
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Series: | Physiological Reports |
Subjects: | |
Online Access: | https://doi.org/10.14814/phy2.15675 |