The therapeutic role and potential mechanism of EGCG in obesity-related precocious puberty as determined by integrated metabolomics and network pharmacology

The therapeutic role and potential mechanism of EGCG in obesity-related precocious puberty as determined by integrated metabolomics and network pharmacology

Objective(-)-Epigallocatechin-3-gallate (EGCG) has preventive effects on obesity-related precocious puberty, but its underlying mechanism remains unclear. The aim of this study was to integrate metabolomics and network pharmacology to reveal the mechanism of EGCG in the prevention of obesity-related...

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Bibliographic Details
Main Authors: Qiuyun Gu, Lina Xia, Qiuju Du, Ying Shao, Jieyi He, Peiying Wu, Lingwei Liang, Xiuhua Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Endocrinology
Subjects:
EGCG
precocious puberty
obesity
metabolomics
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1159657/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1159657/full

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