Nanoparticulate cell-free DNA scavenger for treating inflammatory bone loss in periodontitis

Periodontitis is a common type of inflammatory bone loss, and cell-free DNA (cfDNA) can be a major source that enhances the periodontal tissue destruction. Here, the authors show that a cfDNA-scavenging approach is able to ameliorate periodontitis by using nanoparticulate cfDNA scavenger.

Bibliographic Details
Main Authors: Hanyao Huang, Weiyi Pan, Yifan Wang, Hye Sung Kim, Dan Shao, Baoding Huang, Tzu-Chieh Ho, Yeh-Hsing Lao, Chai Hoon Quek, Jiayu Shi, Qianming Chen, Bing Shi, Shengmin Zhang, Lei Zhao, Kam W. Leong
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33492-6