AZD0530 sensitizes drug‐resistant ALK‐positive lung cancer cells by inhibiting SRC signaling

Most tumors develop resistance to targeted cancer drugs, even though these drugs have produced substantial clinical responses. Here we established anaplastic lymphoma kinase (ALK)‐positive drug‐resistant lung cancer cell lines, which are resistant to ceritinib (LDK378). We found that ceritinib treat...

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Bibliographic Details
Main Authors: Yi Zhao, Yi Yang, Yunhua Xu, Shun Lu, Hong Jian
Format: Article
Language:English
Published: Wiley 2017-04-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12162