The Role of Runx2 in Microtubule Acetylation in Bone Metastatic Breast Cancer Cells

Bone metastasis of breast cancer results in severe bone loss, fractures, and death. Crosstalk between breast cancer cells and bone resident cells promotes osteoclast activity and the release of growth factors from the bone matrix resulting in aggressive tumor growth and bone loss. We and others have...

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Bibliographic Details
Main Authors: Ahmad Othman, Marcus Winogradzki, Shreya Patel, Waddell Holmes, Alan Blank, Jitesh Pratap
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/14/3436