Isolation of Echimidine and Its C-7 Isomers from <i>Echium plantagineum</i> L. and Their Hepatotoxic Effect on Rat Hepatocytes

Isolation of Echimidine and Its C-7 Isomers from <i>Echium plantagineum</i> L. and Their Hepatotoxic Effect on Rat Hepatocytes

Echimidine is the main pyrrolizidine alkaloid of <i>Echium plantagineum</i> L., a plant domesticated in many countries. Because of echimidine’s toxicity, this alkaloid has become a target of the European Food Safety Authority regulations, especially in regard to honey contamination. In t...

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Bibliographic Details
Main Authors: Michał Gleńsk, Marta K. Dudek, Peter Kinkade, Evelyn C. S. Santos, Vitold B. Glinski, Daneel Ferreira, Ewa Seweryn, Sławomir Kaźmierski, Joao B. Calixto, Jan A. Glinski
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
echimidine
echimidine isomers
hepatotoxicity
<i>Echium plantagineum</i> L.
rat hepatocytes primary culture
Online Access:https://www.mdpi.com/1420-3049/27/9/2869

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https://www.mdpi.com/1420-3049/27/9/2869

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