Unbiased Quantitative Single-Cell Morphometric Analysis to Identify Microglia Reactivity in Developmental Brain Injury

Microglia morphological studies have been limited to the process of reviewing the most common characteristics of a group of cells to conclude the likelihood of a “pathological” milieu. We have developed an Imaris-software-based analytical pipeline to address selection and operator biases, enabling u...

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Bibliographic Details
Main Authors: Mark St. Pierre, Sarah Ann Duck, Michelle Nazareth, Camille Fung, Lauren L. Jantzie, Raul Chavez-Valdez
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/13/4/899