Cbfβ regulates Wnt/β-catenin, Hippo/Yap, and Tgfβ signaling pathways in articular cartilage homeostasis and protects from ACLT surgery-induced osteoarthritis

Cbfβ regulates Wnt/β-catenin, Hippo/Yap, and Tgfβ signaling pathways in articular cartilage homeostasis and protects from ACLT surgery-induced osteoarthritis

As the most common degenerative joint disease, osteoarthritis (OA) contributes significantly to pain and disability during aging. Several genes of interest involved in articular cartilage damage in OA have been identified. However, the direct causes of OA are poorly understood. Evaluating the public...

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Bibliographic Details
Main Authors: Wei Chen, Yun Lu, Yan Zhang, Jinjin Wu, Abigail McVicar, Yilin Chen, Siyu Zhu, Guochun Zhu, You Lu, Jiayang Zhang, Matthew McConnell, Yi-Ping Li
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-05-01
Series:eLife
Subjects:
Osteoarthritis
Cbfβ
Wnt signaling
Tgfβ signaling
Yap signaling
AAV mediated treatment of osteoarthritis
Online Access:https://elifesciences.org/articles/95640

Internet

https://elifesciences.org/articles/95640

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