Microbiome dysbiosis is associated with disease duration and increased inflammatory gene expression in systemic sclerosis skin

Microbiome dysbiosis is associated with disease duration and increased inflammatory gene expression in systemic sclerosis skin

Abstract Background Infectious agents have long been postulated to be disease triggers for systemic sclerosis (SSc), but a definitive link has not been found. Metagenomic analyses of high-throughput data allows for the unbiased identification of potential microbiome pathogens in skin biopsies of SSc...

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Bibliographic Details
Main Authors: Michael E. Johnson, Jennifer M. Franks, Guoshuai Cai, Bhaven K. Mehta, Tammara A. Wood, Kimberly Archambault, Patricia A. Pioli, Robert W. Simms, Nicole Orzechowski, Sarah Arron, Michael L. Whitfield
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Arthritis Research & Therapy
Subjects:
Microbiome
Systemic sclerosis
Scleroderma
Metagenomics
RNA-sequencing
Online Access:http://link.springer.com/article/10.1186/s13075-019-1816-z

Internet

http://link.springer.com/article/10.1186/s13075-019-1816-z

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