Administration Routes as Modulators of the Intrahepatic Distribution and Anti-Anemic Activity of Salicylic Acid/Fe3O4 Nanoparticles

Administration Routes as Modulators of the Intrahepatic Distribution and Anti-Anemic Activity of Salicylic Acid/Fe3O4 Nanoparticles

The liver is a key organ in the pharmacokinetics of iron oxide nanoparticles (IONPs). This paper examined how the intravenous (IV) or intragastric (IG) route of administration influenced the intrahepatic distribution or therapeutic effects of IONPs. Wistar rats, some with bleeding-induced anemia, an...

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Bibliographic Details
Main Authors: Bogdan Mîndrilă, Sandra-Alice Buteică, Ion Mîndrilă, Dan-Eduard Mihaiescu, Marina-Daniela Mănescu, Ion Rogoveanu
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomedicines
Subjects:
iron oxide nanoparticles
salicylic acid
administration routes
bleeding-induced anemia
liver zonation
Online Access:https://www.mdpi.com/2227-9059/10/5/1213

Internet

https://www.mdpi.com/2227-9059/10/5/1213

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