Multi-omic underpinnings of epigenetic aging and human longevity

Abstract Biological aging is accompanied by increasing morbidity, mortality, and healthcare costs; however, its molecular mechanisms are poorly understood. Here, we use multi-omic methods to integrate genomic, transcriptomic, and metabolomic data and identify biological associations with four measur...

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Bibliographic Details
Main Authors: Lucas A. Mavromatis, Daniel B. Rosoff, Andrew S. Bell, Jeesun Jung, Josephin Wagner, Falk W. Lohoff
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37729-w