Event Analysis: Using Transcript Events To Improve Estimates of Abundance in RNA-seq Data

Event Analysis: Using Transcript Events To Improve Estimates of Abundance in RNA-seq Data

Alternative splicing leverages genomic content by allowing the synthesis of multiple transcripts and, by implication, protein isoforms, from a single gene. However, estimating the abundance of transcripts produced in a given tissue from short sequencing reads is difficult and can result in both the...

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Bibliographic Details
Main Authors: Jeremy R. B. Newman, Patrick Concannon, Manuel Tardaguila, Ana Conesa, Lauren M. McIntyre
Format: Article
Language:English
Published: Oxford University Press 2018-09-01
Series:G3: Genes, Genomes, Genetics
Subjects:
RNA sequencing
gene expression
transcriptomics
alternative splicing
isoform estimation
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.118.200373

Internet

http://g3journal.org/lookup/doi/10.1534/g3.118.200373

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