Pharmacogenetic analysis of structural variation in the 1000 genomes project using whole genome sequences

Pharmacogenetic analysis of structural variation in the 1000 genomes project using whole genome sequences

Abstract While significant strides have been made in understanding pharmacogenetics (PGx) and gene-drug interactions, there remains limited characterization of population-level PGx variation. This study aims to comprehensively profile global star alleles (haplotype patterns) and phenotype frequencie...

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Bibliographic Details
Main Authors: Carissa A. Sherman, Katrina G. Claw, Seung-been Lee
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Pharmacogenetics
Population genetics
Structural variation
Star alleles
Next-generation sequencing
Online Access:https://doi.org/10.1038/s41598-024-73748-3

Internet

https://doi.org/10.1038/s41598-024-73748-3

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