Mcm10 self-association is mediated by an N-terminal coiled-coil domain.

Minichromosome maintenance protein 10 (Mcm10) is an essential eukaryotic DNA-binding replication factor thought to serve as a scaffold to coordinate enzymatic activities within the replisome. Mcm10 appears to function as an oligomer rather than in its monomeric form (or rather than as a monomer). Ho...

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Bibliographic Details
Main Authors: Wenyue Du, Ajeetha Josephrajan, Suraj Adhikary, Timothy Bowles, Anja-Katrin Bielinsky, Brandt F Eichman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720919?pdf=render