Metabolic drivers of dysglycemia in pregnancy: ethnic-specific GWAS of 146 metabolites and 1-sample Mendelian randomization analyses in a UK multi-ethnic birth cohort

Metabolic drivers of dysglycemia in pregnancy: ethnic-specific GWAS of 146 metabolites and 1-sample Mendelian randomization analyses in a UK multi-ethnic birth cohort

IntroductionGestational diabetes mellitus (GDM) is the most common pregnancy complication worldwide and is associated with short- and long-term health implications for both mother and child. Prevalence of GDM varies between ethnicities, with South Asians (SAs) experiencing up to three times the risk...

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Bibliographic Details
Main Authors: Harriett Fuller, Mark M. Iles, J. Bernadette Moore, Michael A. Zulyniak
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Endocrinology
Subjects:
genetics
GDM
gestational diabetes
South Asian
metabolism
glucose
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1157416/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1157416/full

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