Substance P aggravates ligature-induced periodontitis in mice

Substance P aggravates ligature-induced periodontitis in mice

Periodontitis is one of the most common oral diseases in humans, affecting over 40% of adult Americans. Pain-sensing nerves, or nociceptors, sense local environmental changes and often contain neuropeptides. Recent studies have suggested that nociceptors magnify host response and regulate bone loss...

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Bibliographic Details
Main Authors: Yasir Dilshad Siddiqui, Xuguang Nie, Sheng Wang, Yasaman Abbasi, Lauren Park, Xiaoxuan Fan, Vivek Thumbigere-Math, Man-Kyo Chung
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
Tac1
substance P
periodontitis
mouse model
osteoclasts
cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1099017/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1099017/full

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