Identification of GRIN2D as a novel therapeutic target in pancreatic ductal adenocarcinoma

Identification of GRIN2D as a novel therapeutic target in pancreatic ductal adenocarcinoma

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with a dismal prognosis, and despite significant advances in our understanding of its genetic drivers, like KRAS, TP53, CDKN2A, and SMAD4, effective therapies remain limited. Here, we identified a new therapeutic ta...

Full description

Bibliographic Details
Main Authors: Jiatong Wang, Chi Hin Wong, Yinxin Zhu, Xiaoqiang Yao, Kelvin K C Ng, Chengzhi Zhou, Ka Fai To, Yangchao Chen
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Biomarker Research
Subjects:
Pancreatic ductal adenocarcinoma
Therapeutic target
Oncogene
NMDA receptor
GRIN2D
Online Access:https://doi.org/10.1186/s40364-023-00514-4

Internet

https://doi.org/10.1186/s40364-023-00514-4

Similar Items