Challenges in the Therapeutic Exploitation of Chemokine Receptor-Mediated Internalization of Nanocarriers
Chemokines are small proteins guiding cell migration with crucial role during immune responses. Their actions are mediated by 7-helix trans-membrane Gα protein-coupled receptors and ended by chemokine-receptor complex downregulation. Beyond its physiological role, ligand-induced receptor endocytosis...
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Format: | Article |
Language: | English |
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IMR Press
2024-10-01
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Series: | Frontiers in Bioscience-Landmark |
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Online Access: | https://www.imrpress.com/journal/FBL/29/10/10.31083/j.fbl2910350 |