Challenges in the Therapeutic Exploitation of Chemokine Receptor-Mediated Internalization of Nanocarriers

Chemokines are small proteins guiding cell migration with crucial role during immune responses. Their actions are mediated by 7-helix trans-membrane Gα protein-coupled receptors and ended by chemokine-receptor complex downregulation. Beyond its physiological role, ligand-induced receptor endocytosis...

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Bibliographic Details
Main Author: Giuseppe Bardi
Format: Article
Language:English
Published: IMR Press 2024-10-01
Series:Frontiers in Bioscience-Landmark
Subjects:
Online Access:https://www.imrpress.com/journal/FBL/29/10/10.31083/j.fbl2910350