Arc ubiquitination regulates endoplasmic reticulum-mediated Ca2+ release and CaMKII signaling

Arc ubiquitination regulates endoplasmic reticulum-mediated Ca2+ release and CaMKII signaling

Synaptic plasticity relies on rapid, yet spatially precise signaling to alter synaptic strength. Arc is a brain enriched protein that is rapidly expressed during learning-related behaviors and is essential for regulating metabotropic glutamate receptor-mediated long-term depression (mGluR-LTD). We p...

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Bibliographic Details
Main Authors: Mohammad A. Ghane, Wei Wei, Dina W. Yakout, Zachary D. Allen, Cassandra L. Miller, Bin Dong, Jenny J. Yang, Ning Fang, Angela M. Mabb
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Arc
CaMKII
endoplasmic reticulum
calcium
ubiquitination
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1091324/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1091324/full

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