Deletion of Mettl3 in mesenchymal stem cells promotes acute myeloid leukemia resistance to chemotherapy

Deletion of Mettl3 in mesenchymal stem cells promotes acute myeloid leukemia resistance to chemotherapy

Abstract Acute myeloid leukemia (AML) cell survival and chemoresistance are influenced by the existence of bone marrow mesenchymal stem cells (BMMSCs); however, the pathways by which BMMSCs contribute to these processes remain unclear. We earlier revealed that methyltransferase-like 3 (METTL3) expre...

Full description

Bibliographic Details
Main Authors: Xinai Liao, Danni Cai, Jingru Liu, Haoran Hu, Ruolan You, Zhipeng Pan, Shucheng Chen, Kaiming Xu, Wei Dai, Shuxia Zhang, Xinjian Lin, Huifang Huang
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06325-7

Internet

https://doi.org/10.1038/s41419-023-06325-7

Similar Items