Exploration of drug resistance mechanisms in triple negative breast cancer cells using a microfluidic device and patient tissues

Exploration of drug resistance mechanisms in triple negative breast cancer cells using a microfluidic device and patient tissues

Chemoresistance is a major cause of treatment failure in many cancers. However, the life cycle of cancer cells as they respond to and survive environmental and therapeutic stress is understudied. In this study, we utilized a microfluidic device to induce the development of doxorubicin-resistant (DOX...

Full description

Bibliographic Details
Main Authors: Wanyoung Lim, Inwoo Hwang, Jiande Zhang, Zhenzhong Chen, Jeonghun Han, Jaehyung Jeon, Bon-Kyoung Koo, Sangmin Kim, Jeong Eon Lee, Youngkwan Kim, Kenneth J Pienta, Sarah R Amend, Robert H Austin, Jee-Yin Ahn, Sungsu Park
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-03-01
Series:eLife
Subjects:
microfluidic chip
triple negative breast cancer
polyaneuploid cancer cells
resistance
nuclear protein 1
histone deacetylase 11
Online Access:https://elifesciences.org/articles/88830

Internet

https://elifesciences.org/articles/88830

Similar Items