Application of Green Chemistry Principle in Synthesis of Phenytoin and Its Biogical Evaluation as Anticonvulsant Agents
Phenytoin (5,5'-dipenylimidazolidine-2,4-dione) is the prime example of anticonvulsant agent. According to reported procedure, it is synthesized by condensation of benzil and urea in presence of base (30% w/v NaOH) using ethanol as solvent which itself acts as CNS stimulant. Removal of solvent...
| Главные авторы: | , , |
|---|---|
| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Wiley
2011-01-01
|
| Серии: | E-Journal of Chemistry |
| Online-ссылка: | http://dx.doi.org/10.1155/2011/159430 |