Droplet digital PCR-based analyses for robust, rapid, and sensitive molecular diagnostics of gliomas

Droplet digital PCR-based analyses for robust, rapid, and sensitive molecular diagnostics of gliomas

Abstract Classification of gliomas involves the combination of histological features with molecular biomarkers to establish an integrated histomolecular diagnosis. Here, we report on the application and validation of a set of molecular assays for glioma diagnostics based on digital PCR technology us...

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Bibliographic Details
Main Authors: Marietta Wolter, Jörg Felsberg, Bastian Malzkorn, Kerstin Kaulich, Guido Reifenberger
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Acta Neuropathologica Communications
Subjects:
DNA copy number variation
Droplet digital PCR
Glioma
Molecular diagnostics
Mutation
Single nucleotide variation
Online Access:https://doi.org/10.1186/s40478-022-01335-6

Internet

https://doi.org/10.1186/s40478-022-01335-6

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