In Vitro Evaluation of Drug–Drug Interaction Potential of Epetraborole, a Novel Bacterial Leucyl-tRNA Synthetase Inhibitor

Epetraborole (EBO) is a boron-containing inhibitor of bacterial leucyl-tRNA synthetase, with potent activity against nontuberculous mycobacteria (NTM) and Gram-negative bacteria, including <i>Burkholderia pseudomallei</i>. EBO is being developed for the treatment of NTM lung disease and...

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Main Authors: Afshin Shafiee, Sanjay Chanda
格式: 文件
语言:English
出版: MDPI AG 2024-01-01
丛编:Pharmaceuticals
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在线阅读:https://www.mdpi.com/1424-8247/17/1/120