Molecular test of Paget's disease of bone in families not linked to SQSTM1 gene mutations

Molecular test of Paget's disease of bone in families not linked to SQSTM1 gene mutations

Purpose: Paget's disease of bone (PDB) is a focal metabolic bone disorder characterized by an increased bone remodeling. Fifteen to 40 % of PDB patients have a familial form with an autosomal dominant inheritance. Disease-causing mutations of the SQSTM1 gene have been linked to PDB in about 40 ...

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Bibliographic Details
Main Authors: Yang You, David Simonyan, Alexandre Bureau, Edith Gagnon, Caroline Albert, Jason R. Guertin, Jean-Eric Tarride, Jacques P. Brown, Laëtitia Michou
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Bone Reports
Subjects:
Paget's disease of bone
Family history
Precision medicine
Biomarker
Logistic regression
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187223000189

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http://www.sciencedirect.com/science/article/pii/S2352187223000189

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