Reprogramming histone modification patterns to coordinate gene expression in early zebrafish embryos

Abstract Background Multicellular organisms require precise gene regulation during ontogeny, and epigenetic modifications, such as DNA methylation and histone modification, facilitate this precise regulation. The conservative reprogramming patterns of DNA methylation in vertebrates have been well de...

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Bibliographic Details
Main Authors: Wei Zhu, Xiaocui Xu, Xinxin Wang, Jiang Liu
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-019-5611-7