Germline DNA damage repair gene mutations in pancreatic cancer patients with personal/family histories of pancreas/breast/ovarian/prostate cancer in a Japanese population

Germline DNA damage repair gene mutations in pancreatic cancer patients with personal/family histories of pancreas/breast/ovarian/prostate cancer in a Japanese population

Abstract Aim Cancer patients with personal/family histories of pancreatic/breast/ovarian/prostate cancer are associated with a higher likelihood of harboring DNA damage repair (DDR)‐related germline mutations. Here, we aimed to obtain a better understanding of DDR‐related germline mutations in Japan...

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Bibliographic Details
Main Authors: Tatsuo Hata, Masamichi Mizuma, Fuyuhiko Motoi, Masaharu Ishida, Hideo Ohtsuka, Kei Nakagawa, Takanori Morikawa, Toru Furukawa, Michiaki Unno
Format: Article
Language:English
Published: Wiley 2021-11-01
Series:Annals of Gastroenterological Surgery
Subjects:
familial pancreatic cancer
germline mutation
homologous recombination repair
mismatch repair
next‐generation sequencing
Online Access:https://doi.org/10.1002/ags3.12482

Internet

https://doi.org/10.1002/ags3.12482

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