Syringaresinol Alleviates Oxaliplatin-Induced Neuropathic Pain Symptoms by Inhibiting the Inflammatory Responses of Spinal Microglia

Syringaresinol Alleviates Oxaliplatin-Induced Neuropathic Pain Symptoms by Inhibiting the Inflammatory Responses of Spinal Microglia

Oxaliplatin-induced peripheral neuropathy (OIPN) is a serious side effect that impairs the quality of life of patients treated with the chemotherapeutic agent, oxaliplatin. The underlying pathophysiology of OIPN remains unclear, and there are no effective therapeutics. This study aimed to investigat...

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Bibliographic Details
Main Authors: Ji Hwan Lee, Jong Hee Choi, Jaihwan Kim, Tai Wan Kim, Ji-Young Kim, Geehoon Chung, Ik-Hyun Cho, Dae Sik Jang, Sun Kwang Kim
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
inflammation
microglia
neuropathic pain
oxaliplatin
phytochemical
syrinagresinol
Online Access:https://www.mdpi.com/1420-3049/27/23/8138

Internet

https://www.mdpi.com/1420-3049/27/23/8138

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