Point Mutations in RET Proto-Oncogene Exon 10 in Patients with Medullary Thyroid Carcinoma

Point Mutations in RET Proto-Oncogene Exon 10 in Patients with Medullary Thyroid Carcinoma

Background & Aims: Thyroid cancer is the most common endocrine malignancy. Medullary thyroid carcinoma (MTC) is an aggressive malignant tumor arising from parafollicular cells of the thyroid. MTC occurs in hereditary (25%, hMTC) or sporadic (75%, sMTC) forms. The hMTC form has an autosomal domin...

Full description

Bibliographic Details
Main Authors: Marjan Zarif-Yeganeh, Sara Sheikholeslami, Golnoush Dehbashi-Behbahani, Samaneh Farashi, Laleh Hoghooghi-Rad, Fereidoun Azizi, Mehdi Hedayati
Format: Article
Language:English
Published: Kerman University of Medical Sciences 2015-05-01
Series:Journal of Kerman University of Medical Sciences
Subjects:
medullary thyroid cancer
ret proto-oncogene
exon 10
germline mutation
iranian population
Online Access:https://jkmu.kmu.ac.ir/article_16108_928a74159f624fc856bed2d52f2926f6.pdf

Internet

https://jkmu.kmu.ac.ir/article_16108_928a74159f624fc856bed2d52f2926f6.pdf

Similar Items