Human Platelet Lysate Can Replace Fetal Calf Serum as a Protein Source to Promote Expansion and Osteogenic Differentiation of Human Bone-Marrow-Derived Mesenchymal Stromal Cells

Human Platelet Lysate Can Replace Fetal Calf Serum as a Protein Source to Promote Expansion and Osteogenic Differentiation of Human Bone-Marrow-Derived Mesenchymal Stromal Cells

Fetal calf serum (FCS) is frequently used as a growth factor and protein source in bone-marrow-derived mesenchymal stromal cell (BMSC) culture media, although it is a xenogenic product presenting multiple disadvantages including but not limited to ethical concerns. A promising alternative for FCS is...

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Bibliographic Details
Main Authors: Maria Karadjian, Anne-Sophie Senger, Christopher Essers, Sebastian Wilkesmann, Raban Heller, Joerg Fellenberg, Rolf Simon, Fabian Westhauser
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
osteogenic differentiation
population doublings
human mesenchymal stromal cells
fetal calf serum
human platelet lysate
Online Access:https://www.mdpi.com/2073-4409/9/4/918

Internet

https://www.mdpi.com/2073-4409/9/4/918

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