Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase
Abstract Histone lysine methyltransferase SUV420H1, which is responsible for site-specific di-/tri-methylation of histone H4 lysine 20 (H4K20), has crucial roles in DNA-templated processes, including DNA replication, DNA damage repair, and chromatin compaction. Its mutations frequently occur in huma...
| Những tác giả chính: | , , , , , , , |
|---|---|
| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
| Được phát hành: |
Nature Publishing Group
2023-12-01
|
| Loạt: | Cell Discovery |
| Truy cập trực tuyến: | https://doi.org/10.1038/s41421-023-00620-5 |